A cross-country road trip is the ultimate adventure, offering breathtaking scenery, historic landmarks, and unforgettable experiences. Whether you prefer coastal highways, mountain passes, or open desert roads, these routes showcase the best of the United States.

1. Route 66 – Chicago to Santa Monica
No list of cross-country road trips is complete without Route 66. Known as the “Mother Road,” this legendary highway stretches from Chicago, Illinois, to Santa Monica, California. Along the way, you’ll pass classic diners, quirky roadside attractions, and ghost towns that tell the story of America’s past. Stops like Cadillac Ranch in Texas, the Petrified Forest in Arizona, and the Santa Monica Pier make this route iconic.
2. The Great Northern – U.S. Highway 2
For a scenic drive through the northern U.S., Highway 2 offers a spectacular route from Washington to Maine. This less-traveled road runs near the Canadian border, passing through Glacier National Park, the Great Lakes, and the rugged landscapes of Montana and North Dakota. The mix of mountain views, rolling farmland, and historic small towns makes this a peaceful and scenic journey.
3. The Loneliest Road – U.S. Highway 50
Stretching from California to Maryland, U.S. Highway 50 takes you through some of the most remote parts of the country. The Nevada section, famously called “The Loneliest Road in America,” offers vast desert landscapes, old mining towns, and stunning mountain views. This route is perfect for those who enjoy solitude and adventure.
4. The Pacific Coast Highway – California to Washington
For breathtaking ocean views, the Pacific Coast Highway (PCH) is unbeatable. Starting in San Diego, California, and stretching north to Olympia, Washington, this route follows the dramatic coastline of the Pacific Ocean. Highlights include the Golden Gate Bridge, Big Sur, Oregon’s rugged beaches, and the Olympic Peninsula. It’s a dream drive for nature lovers.
5. The Appalachian Trail Drive – Maine to Georgia
If you prefer rolling mountains and lush forests, this east coast road trip follows the Appalachian Mountains from Maine to Georgia. The journey includes stops at Shenandoah National Park, the Great Smoky Mountains, and historic small towns. The winding roads and scenic overlooks make this a peaceful yet adventurous trip.
6. The Southern Route – Interstate 10
For a warmer cross-country trip, Interstate 10 runs from Los Angeles, California, to Jacksonville, Florida. This route takes you through the deserts of Arizona, the vibrant culture of New Orleans, and the Gulf Coast beaches of Texas and Florida. It’s a great choice for those who love warm weather and diverse landscapes.
7. The Border-to-Border Route – U.S. Highway 93
If you want to drive from Canada to Mexico, Highway 93 is an incredible choice. This route starts in Montana and stretches south to Arizona, passing through Glacier National Park, the Rocky Mountains, and the deserts of Nevada. It’s a rugged and scenic drive, perfect for those who love adventure and wide-open spaces.
8. The Trans-America Trail – Off-Road Adventure
For the ultimate off-road challenge, the Trans-America Trail (TAT) runs from North Carolina to Oregon, covering gravel roads, mountain trails, and desert tracks. This route is ideal for off-road vehicles and motorcyclists looking for an unforgettable backcountry experience. It’s a true test of endurance and adventure.
9. The Lincoln Highway – Coast to Coast
As the first transcontinental highway in the U.S., the Lincoln Highway stretches from Times Square in New York City to San Francisco, California. It follows a mix of highways and scenic byways, taking you through farmlands, mountains, and historic towns. This route is perfect for those who love history and classic Americana.
10. The Gulf Coast Road Trip – Florida to Texas
For a relaxed coastal drive, the Gulf Coast route follows the southern shoreline from Florida to Texas. You’ll pass through New Orleans, Mobile, and Galveston, with plenty of chances to enjoy fresh seafood, sandy beaches, and vibrant culture. This is a great trip for those who love ocean views and laid-back vibes.
Conclusion
A cross-country road trip is an adventure of a lifetime. Whether you prefer historic highways, coastal drives, or remote desert roads, there’s a perfect route waiting for you. Pack your bags, fuel up, and get ready to explore the beauty of the United States one mile at a time.